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GHS / HazCom term · Glossary

Skin Corrosion

Verified vs OSHA sources · 2026-10-05

A GHS health-hazard class for chemicals that cause irreversible damage to the skin — visible necrosis through the epidermis into the dermis — after up to 4 hours of contact. Corrosion is Category 1 (sub-divided 1A/1B/1C by how fast it acts); the milder, reversible effect is skin irritation (Category 2). Corrosives carry the corrosion pictogram (GHS05).

29 CFR 1910.1200 App A.2

Also known as: skin corrosion/irritation

Skin Corrosion at a glance

  • Corrosion = irreversible damage (Category 1); irritation = reversible (Category 2).
  • Category 1 sub-divides into 1A/1B/1C based on how quickly the damage occurs.
  • Corrosion uses GHS05 (corrosion) + “Danger” + H314; irritation uses GHS07 + “Warning” + H315.
  • Extreme pH (≤2 or ≥11.5) is often a strong indicator of corrosivity.

In plain English

How GHS rates a chemical that burns or eats into skin. If the damage is permanent it's “corrosion” (Category 1); if it's reversible redness/swelling it's “irritation” (Category 2). Strong acids and bases are classic corrosives.

What the source says, in summary

Skin corrosion is the production of irreversible damage to the skin; namely, visible necrosis through the epidermis and into the dermis, following the application of a test substance for up to 4 hours.
29 CFR 1910.1200 App A.2.1Summarized, not quoted: read the source for its operative wording.

In context

A classification or labeling concept from the UN Globally Harmonized System, adopted into US law through OSHA's Hazard Communication Standard (29 CFR 1910.1200) and its appendices.

29 CFR 1910.1200

Where this is written in OSHA's rules

Example

Concentrated sodium hydroxide causes irreversible skin necrosis within minutes, so it's classified skin corrosion Category 1A — label pictogram GHS05 (corrosion), signal word “Danger,” and H314, “Causes severe skin burns and eye damage.” A mild detergent that only reddens skin would be Category 2 (irritation), H315.

Why it matters

Skin corrosion drives both the corrosion pictogram and the PPE (gloves, face/eye protection) workers need. Calling a corrosive a mere “irritant,” or omitting GHS05, understates a burn hazard and is a HazCom classification/labeling violation under 1910.1200.

Skin corrosion vs. skin irritation vs. sensitization

Corrosion is irreversible chemical burning (Category 1). Irritation is reversible inflammation (Category 2). Skin sensitization is an allergic immune reaction that develops over time — a different hazard class (GHS07, H317) entirely.

GHS skin corrosion / irritation

EffectCategoryPictogram · H-code
Corrosion (irreversible)1 (sub 1A / 1B / 1C)Corrosion (GHS05) · H314
Irritation (reversible)2Exclamation (GHS07) · H315
Mild irritation3 (not adopted by OSHA)(none) · H316

Skin Corrosion: frequently asked questions

What is the difference between skin corrosion and skin irritation?
Skin corrosion is irreversible damage (necrosis into the dermis) — GHS Category 1, pictogram GHS05, H314. Skin irritation is reversible inflammation — Category 2, pictogram GHS07, H315.
What do the 1A, 1B, and 1C sub-categories mean?
They divide Category 1 corrosion by how quickly it acts: 1A within 3 minutes of exposure, 1B between 3 minutes and 1 hour, and 1C between 1 and 4 hours. OSHA allows using just “Category 1” when the data don't distinguish them.
Does extreme pH automatically make a chemical corrosive?
A pH at or below 2 or at or above 11.5 is strong evidence of corrosivity, but acid/alkali reserve (buffering capacity) is also considered. Section 9 of the SDS lists pH.

Related terms

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Governing OSHA standards

More GHS terms

Acute Toxicity

A GHS health-hazard class for the harmful effects that follow a single dose, several doses within 24 hours, or a 4-hour inhalation exposure. Chemicals are sorted into categories by route (oral, dermal, inhalation) using LD50/LC50 cut-offs — Category 1 is the most toxic. OSHA's HazCom standard uses Categories 1–4.

Aspiration Hazard

A GHS health-hazard class for chemicals that can be fatal if swallowed and then enter the airways — directly or by vomiting — causing chemical pneumonia or lung injury. Thin, low-viscosity hydrocarbons (gasoline, kerosene, lamp oil) are the classic example. It is Category 1, with the health-hazard pictogram (GHS08) and signal word “Danger.”

Carcinogenicity

A GHS health-hazard class for chemicals that cause cancer or increase its incidence. GHS (and OSHA's HazCom standard) sorts carcinogens into Category 1A (known human carcinogen), 1B (presumed, from animal evidence), and Category 2 (suspected). Carcinogens carry the health-hazard pictogram (GHS08) and a hazard statement such as H350 (“May cause cancer”).

Chemicals Under Pressure

A physical-hazard class added by OSHA's 2024 HCS update (aligning with GHS Revision 7) for liquids or solids pressurized with a gas, held in pressure receptacles other than aerosol dispensers and not classified as gases under pressure. It is categorized by the flammability of its contents and always carries the gas-cylinder pictogram (GHS04) for the pressure hazard.

Classification

The process of evaluating the available scientific evidence for a chemical against the GHS criteria to decide whether it is hazardous and, if so, the hazard class and category of each effect. Classification is the first step in HazCom — its result determines every label element (pictogram, signal word, hazard and precautionary statements) and SDS content.

Corrosive to Metals

A GHS physical-hazard class for chemicals that, by chemical action, will materially damage or even destroy metals. It is a single category (Category 1), determined by corrosion-rate testing on steel and aluminum, and uses the corrosion pictogram (GHS05) with the hazard statement H290. It is a separate hazard from skin corrosion, even though both use GHS05.

Desensitized Explosives

A physical-hazard class added by OSHA's 2024 HCS update (GHS Revision 7) for solid or liquid explosives that have been phlegmatized — wetted or diluted — to suppress their explosive properties for safe transport and storage. It has four categories based on the corrected burning rate, and uses the flame pictogram (GHS02), not the exploding-bomb.

Globally Harmonized System (GHS)

An internationally agreed framework created by the United Nations (first adopted in 2003) that standardizes how chemical hazards are classified and communicated — using common hazard classes, pictograms, signal words (Danger / Warning), and coded hazard (H) and precautionary (P) statements on labels and safety data sheets. The US adopted GHS into law through OSHA's 2012 Hazard Communication Standard update.

Sources & verification

Reviewed by HazComFast against eCFR, OSHA.gov, NIOSH, and the Federal Register. Last reviewed 2026-10-05. This glossary is general information, not legal advice; OSHA State-Plan states (e.g. California, Michigan) may adopt stricter requirements.

Put Skin Corrosion into practice

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