GHS / HazCom term · Glossary
Pyrophoric
Verified vs OSHA sources · 2026-10-05
A chemical that ignites spontaneously in air — no spark or flame needed. Under GHS/HazCom, a pyrophoric liquid or solid is one liable to ignite within five minutes after coming into contact with air, even in small quantities. (A pyrophoric gas ignites spontaneously in air at or below 54°C.) Pyrophorics carry the GHS02 flame pictogram and demand inert handling (nitrogen/argon blanketing).
Also known as: pyrophoric liquid, pyrophoric solid, air-reactive
On this page
Pyrophoric at a glance
- Ignites within 5 minutes of air contact — even in small quantities.
- Single hazard category (Category 1) for pyrophoric liquids and for pyrophoric solids.
- Pyrophoric gas is defined separately: ignites spontaneously in air at ≤ 54°C (130°F).
- Handled under inert atmosphere; GHS02 flame pictogram, signal word “Danger.”
In plain English
A material that bursts into flame the moment it touches air — within five minutes, without any ignition source. Because of that, pyrophorics are handled under an inert gas (like nitrogen) and never exposed to open air.
What the rule says
“Pyrophoric liquid means a liquid which, even in small quantities, is liable to ignite within five minutes after coming into contact with air.”
In context
A classification or labeling concept from the UN Globally Harmonized System, adopted into US law through OSHA's Hazard Communication Standard (29 CFR 1910.1200) and its appendices.
Where this is written in OSHA's rules
- 29 CFR 1910.1200 App B.9Read on eCFR / OSHA.gov
Example
Tert-butyllithium, a reagent used in organic synthesis, is pyrophoric — it ignites on contact with air — so it's transferred by syringe under argon. Finely divided metals like white phosphorus and some metal hydrides are pyrophoric solids for the same reason.
Why it matters
Pyrophorics remove the ignition source from the fire equation: exposure to air alone starts the fire. That makes a breached container, a wet glove, or a careless transfer an immediate flash-fire risk — which is why the standard flags them at the highest fire-hazard tier and why lab and industrial handling relies on inert-atmosphere technique.
Pyrophoric vs. self-heating
Both self-ignite via reaction with air, but the speed and scale differ. A pyrophoric ignites within 5 minutes, even in small quantities. A self-heating chemical ignites only in large amounts (kilograms) and over long periods (hours or days). Pyrophoric = fast and small; self-heating = slow and bulk.
Forms of pyrophoric chemicals
| Form | Criterion |
|---|---|
| Pyrophoric liquid | Ignites within 5 min of air contact (even small amounts) |
| Pyrophoric solid | Ignites within 5 min of air contact (even small amounts) |
| Pyrophoric gas | Ignites spontaneously in air at ≤ 54°C (130°F) |
Pyrophoric: frequently asked questions
- What does pyrophoric mean?
- That a chemical ignites spontaneously in air. For pyrophoric liquids and solids, GHS defines it as igniting within five minutes after contact with air, even in small quantities — no spark or flame required.
- How is a pyrophoric different from a self-heating substance?
- A pyrophoric ignites fast (within 5 minutes) and even in small quantities. A self-heating chemical ignites only in large amounts and after long periods (hours or days). Both react with air, but at very different speeds and scales.
- How are pyrophoric chemicals handled safely?
- Under an inert atmosphere — blanketed with nitrogen or argon and transferred without air exposure (e.g., by syringe or cannula) — because any contact with air can ignite them.
Related terms
Free tools for this
Governing OSHA standards
More GHS terms
A GHS health-hazard class for the harmful effects that follow a single dose, several doses within 24 hours, or a 4-hour inhalation exposure. Chemicals are sorted into categories by route (oral, dermal, inhalation) using LD50/LC50 cut-offs — Category 1 is the most toxic. OSHA's HazCom standard uses Categories 1–4.
Aspiration HazardA GHS health-hazard class for chemicals that can be fatal if swallowed and then enter the airways — directly or by vomiting — causing chemical pneumonia or lung injury. Thin, low-viscosity hydrocarbons (gasoline, kerosene, lamp oil) are the classic example. It is Category 1, with the health-hazard pictogram (GHS08) and signal word “Danger.”
CarcinogenicityA GHS health-hazard class for chemicals that cause cancer or increase its incidence. GHS (and OSHA's HazCom standard) sorts carcinogens into Category 1A (known human carcinogen), 1B (presumed, from animal evidence), and Category 2 (suspected). Carcinogens carry the health-hazard pictogram (GHS08) and a hazard statement such as H350 (“May cause cancer”).
Chemicals Under PressureA physical-hazard class added by OSHA's 2024 HCS update (aligning with GHS Revision 7) for liquids or solids pressurized with a gas, held in pressure receptacles other than aerosol dispensers and not classified as gases under pressure. It is categorized by the flammability of its contents and always carries the gas-cylinder pictogram (GHS04) for the pressure hazard.
ClassificationThe process of evaluating the available scientific evidence for a chemical against the GHS criteria to decide whether it is hazardous and, if so, the hazard class and category of each effect. Classification is the first step in HazCom — its result determines every label element (pictogram, signal word, hazard and precautionary statements) and SDS content.
Corrosive to MetalsA GHS physical-hazard class for chemicals that, by chemical action, will materially damage or even destroy metals. It is a single category (Category 1), determined by corrosion-rate testing on steel and aluminum, and uses the corrosion pictogram (GHS05) with the hazard statement H290. It is a separate hazard from skin corrosion, even though both use GHS05.
Desensitized ExplosivesA physical-hazard class added by OSHA's 2024 HCS update (GHS Revision 7) for solid or liquid explosives that have been phlegmatized — wetted or diluted — to suppress their explosive properties for safe transport and storage. It has four categories based on the corrected burning rate, and uses the flame pictogram (GHS02), not the exploding-bomb.
Globally Harmonized System (GHS)An internationally agreed framework created by the United Nations (first adopted in 2003) that standardizes how chemical hazards are classified and communicated — using common hazard classes, pictograms, signal words (Danger / Warning), and coded hazard (H) and precautionary (P) statements on labels and safety data sheets. The US adopted GHS into law through OSHA's 2012 Hazard Communication Standard update.
Sources & verification
- 29 CFR 1910.1200 App B.9 (eCFR / OSHA.gov)
- OSHA — 1910.1200 Appendix B.9/B.10 (Pyrophoric Liquids/Solids)
- OSHA — Hazard Communication (Physical Hazards)
Reviewed by HazComFast against eCFR, OSHA.gov, NIOSH, and the Federal Register. Last reviewed 2026-10-05. This glossary is general information, not legal advice; OSHA State-Plan states (e.g. California, Michigan) may adopt stricter requirements.
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