General safety term · Glossary
CAS Number
A unique numerical identifier assigned by the Chemical Abstracts Service (a division of the American Chemical Society) to every distinct chemical substance. It has the format of up to seven digits, a dash, two digits, a dash, and a final check digit (e.g., 67-64-1 for acetone). Because chemical names vary, the CAS number is the unambiguous global key used on SDSs, inventories, and regulations.
Also known as: CAS Registry Number, CAS RN, CASRN
On this page
CAS Number at a glance
- Uniquely identifies one substance regardless of naming or language.
- Format: up to 7 digits – 2 digits – 1 check digit (e.g., 67-64-1).
- The last digit is a check digit that validates the number.
- Appears in SDS Section 3 and is used across inventories and regulations.
In plain English
A chemical's fingerprint number. One substance can have many names (acetone, propanone, dimethyl ketone), but only one CAS number (67-64-1). It's how you look up the exact same chemical no matter what a label calls it.
What the source says, in summary
A CAS Registry Number is a unique numerical identifier assigned by the Chemical Abstracts Service to every chemical substance described in the open scientific literature; it identifies a specific substance regardless of its many possible names.
In context
An industrial-hygiene, exposure-control, or program-management concept that applies across OSHA standards and workplaces.
Example
Acetone's CAS number is 67-64-1. Whether a label says “acetone,” “2-propanone,” or “dimethyl ketone,” the CAS 67-64-1 confirms it's the same chemical — so a hygienist or responder can pull the right exposure limits and hazard data every time.
Why it matters
Chemical names are ambiguous and translate differently, but a CAS number is exact — which is why SDSs, chemical inventories, TRI reporting, and exposure-limit tables all key off it. Matching by name instead of CAS number is how the wrong hazard data or exposure limit gets applied to a chemical.
CAS number vs. UN number vs. product identifier
A CAS number identifies a specific chemical substance (for science/regulation). A UN number identifies a material for transport (and can cover a category). A product identifier is whatever name/number ties a label to its SDS. A single product can carry all three.
Reading a CAS number (67-64-1, acetone)
| Segment | Digits | Role |
|---|---|---|
| First part | Up to 7 (here “67”) | Sequentially assigned base number |
| Second part | 2 (here “64”) | Continuation of the identifier |
| Check digit | 1 (here “1”) | Validates the number mathematically |
CAS Number: frequently asked questions
- What is a CAS number?
- A unique numerical identifier assigned by the Chemical Abstracts Service to every chemical substance, in the format up-to-7-digits – 2-digits – 1-check-digit (e.g., 67-64-1 for acetone). It identifies a substance regardless of what name is used.
- Where do I find the CAS number on an SDS?
- In Section 3 (Composition / information on ingredients), which lists each hazardous ingredient with its CAS number so it can be looked up unambiguously.
- What's the difference between a CAS number and a UN number?
- A CAS number identifies a specific chemical substance for scientific and regulatory reference; a UN number identifies a material for transport and emergency response. A product can have both.
Related terms
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Governing OSHA standards
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Ceiling LimitAn exposure limit that must not be exceeded at any instant during the workday — the strictest type of OSHA exposure limit. In OSHA's Z-tables it is marked with a “C” before the value. Unlike an 8-hour TWA (an average) or a 15-minute STEL, a ceiling applies to a single moment.
Chemical CompatibilityWhether two or more chemicals can be safely stored or used near each other without reacting dangerously — releasing heat, toxic gas, or fire. Incompatible chemicals must be physically separated (segregated) in storage. Each chemical's incompatibilities are listed in Section 10 of its SDS, and compatibility drives storage layout and spill response.
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Sources & verification
Reviewed by HazComFast against eCFR, OSHA.gov, NIOSH, and the Federal Register. Last reviewed 2026-10-05. This glossary is general information, not legal advice; OSHA State-Plan states (e.g. California, Michigan) may adopt stricter requirements.
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