What 29 CFR 1910.101 requires (plain English)
29 CFR 1910.101 sets the general requirements for the handling, storage, and use of compressed gases in cylinders in general industry. Its foundation is the employer's duty to determine, by visual inspection, that cylinders under its control are in a safe condition, and to follow the established consensus standards for compressed gas safety.
The standard incorporates the Compressed Gas Association's safety practices by reference and works with the specific requirements for gas cylinders elsewhere in the regulations: cylinders must be secured upright to prevent them from falling, valve protection caps kept in place when cylinders are not connected and in use, and cylinders protected from damage, heat, and tampering. Oxygen and fuel-gas cylinders must be separated in storage.
1910.101 is part of Subpart H (hazardous materials) and works alongside the standards for specific gases (oxygen, acetylene, and LP-gas (1910.110)) and the welding standards (1910.253) that govern how cylinders are used in cutting and welding. It is the baseline for treating every cylinder as the pressure vessel it is.