What 29 CFR 1910.1043 requires (plain English)
29 CFR 1910.1043 protects workers in the textile industry from cotton dust: the dust generated when cotton is processed from bale to yarn and fabric. Inhaling it causes byssinosis, or brown lung, a respiratory disease whose hallmark is chest tightness and breathlessness that is worst on the first day back at work ("Monday chest tightness") and that can become permanent.
The standard sets process-specific permissible exposure limits measured as lint-free respirable cotton dust over an 8-hour time-weighted average: 200 µg/m³ for yarn manufacturing (and cotton washing), with higher limits for slashing and weaving operations and for waste-house and other processing. Employers must monitor exposures, use engineering and work-practice controls (ventilation, enclosure, washed cotton), provide respirators where controls are insufficient, and conduct medical surveillance with pulmonary function testing.
1910.1043 is a Subpart Z substance-specific health standard. It was central to the Supreme Court's 1981 "Cotton Dust" decision (American Textile Manufacturers Institute v. Donovan), which upheld OSHA's authority to set health standards without a strict cost-benefit test: a landmark in occupational health law.